- Treatment for erectile dysfunction with Spedra®
- Access Spedra® following an online medical consultation
- What is Spedra®?
- What is the active substance in Spedra®?
- Who can be considered for treatment with Spedra®?
- What strengths are available?
- Can I change my dose?
- How is Spedra® taken?
- What can affect the effect of Spedra®?
- When should Spedra® not be used?
- Warnings and precautions
- Interactions with other medicines, food and drink
- What side effects can occur?
- Spedra® active substance and excipients
- Patient information leaflet
Treatment for erectile dysfunction with Spedra®
Spedra® is a prescription-only medicine for erectile dysfunction (ED) in adult men. Erectile dysfunction isthe persistent inability to achieve or maintain an erection sufficient for satisfactory sexual activity.
Spedra® contains avanafil, a phosphodiesterase type-5 (PDE-5) inhibitor that works by increasing blood flow to the penis during sexual stimulation.It does not cause an erection without sexual stimulation..
Spedra® is notable for its rapid onset of action. The appropriate dose is determined by a UK-registered prescriber following a medical assessment.
Access Spedra® following an online medical consultation
Complete a confidential medical questionnaire through our online consultation service.
A UK-registered prescriber will review your responses and if Spedra® is clinically appropriate,issue a prescription
Important information
DoktorABC UK is a digital health platform that connects patients with independent, UK-registered prescribers. DoktorABC UK does not itself provide medical care, issue prescriptions or dispense medicines. All clinical decisions are made by the UK-registered prescriber following an individual medical assessment.
What is Spedra®?
Spedra® is a prescription medicine for erectile dysfunction in adult men. It supports the natural erectile response by relaxing blood vessels in the penis and improving blood flow during sexual stimulation.
Spedra® can take effect in as little as 15–30 minutes . and last for up to six hours, though this varies between men.
What is the active substance in Spedra®?
The active substance is avanafil, aPDE-5 inhibitor,, which regulates blood flow in the penis,enhancing the natural erectile response to sexual stimulation
Who can be considered for treatment with Spedra®?
Spedra® may be considered for adult men aged 18 and over with erectile dysfunction following a medical assessment.
A UK-registered prescriber will consider cardiovascular health and fitness for sexual activity, current medicines, (including nitrates), and relevant medical history, including liver or kidney function and eye conditions
Treatment is not be suitable for everyone.
What strengths are available?
Spedra® is available in 50 mg, 100 mg, and 200 mg.
The usual starting dose is 100 mg, taken approximately 15–30 minutes before sexual activity. Dose adjustments are made by the UK-registered prescriber depending on effectiveness and tolerability.
Can I change my dose?
No. Any dose adjustment should be made in consultation with the UK-registered prescriber.
How should I take Spedra®?
Always take Spedra® exactly as prescribed and in accordance with the patient information leaflet.
Take one tablet approximately 15–30 minutes before sexual activity, swallowed whole with water. It can be taken with or without food. Do not take more than one tablet per day. Sexual stimulation is required for Spedra® to work.
Alcohol may increase the risk of side effects and may reduce erectile response.
What can affect how well Spedra® works?
A number of factors may influence your response to Spedra®, including underlying health conditions (such as diabetes or cardiovascular disease), certain medicines, and incorrect timing or dosage. Heavy alcohol consumption may reduce erectile function and increase the risk of side effects. Your UK-registered prescriber can advise if you are concerned.
When should Spedra® not be used?
Do not take Spedra® if you:
- Are allergic to avanafil or any of its ingredients.
- Take nitrate medicines for chest pain (angina), or use nitric oxide donors such as amyl nitrite ("poppers").
- Take riociguat.
- Have recently had a heart attack or stroke.
- Have severe heart, liver or kidney disease.
- Have very low blood pressure.
- Have certain serious eye conditions.
Spedra® is not suitable for women or men under 18.
Always tell your UK-registered prescriber about your full medical history and current medicines before starting treatment.
Warnings and precautions
Speak to a UK-registered prescriber before using Spedra® if you:
- Have heart problems or have been advised to avoid sexual activity.
- Have kidney or liver impairment.
- Have blood disorders such as sickle cell anaemia, leukaemia or multiple myeloma.
- Have an anatomical deformation of the penis or Peyronie's disease.
- Have a stomach ulcer or bleeding disorder.
- Notice sudden changes in your vision or hearing.
Spedra® should not be used alongside other treatments for erectile dysfunction unless specifically advised by a UK-registered prescriber.
Interactions with other medicines, food and drink
Tell your UK-registered prescriber if you take medicines for high blood pressure, alpha blockers, antifungals, medicines for HIV, certain antibiotics, or any other erectile dysfunction treatment.
Alcohol may increase the risk of side effects.
What side effects can occur?
Like all medicines, Spedra® can cause side effects, although not everyone experiences them.
Common side effects may include:
- Headache
- Dizziness
- Flushing
- Nasal congestion
- Feeling warm
Less common side effects may include:
- Fatigue
- Shortness of breath on exertion
- Indigestion
- Increased heart rate
Serious side effects (seek urgent medical help):
- Prolonged or painful erection lasting more than four hours (priapism).
- Sudden loss of vision or hearing.
- Severe allergic reactions such as swelling of face, lips or throat, or breathing difficulties.
Reporting side effects (UK)
Suspected adverse reactions can be reported via the MHRA Yellow Card scheme or by searching for MHRA Yellow Card in the Google Play or Apple App Store.
Driving and operating machinery
Spedra® may cause dizziness in some people. Do not drive or operate heavy machinery if affected.
Storage information
- Keep out of the sight and reach of children.
- Do not use after the expiry date shown on the packaging.
- Store in the original packaging as directed in the patient information leaflet.
- Dispose of unused medicines safely; ask a pharmacist if unsure.
Spedra® active substance and excipients
The active substance is avanafil (50 mg, 100 mg or 200 mg tablets). Excipients vary by strength. Full ingredient lists and marketing authorisation holder details are available in the UK patient information leaflet.
Excipients vary by strength.
Full ingredient lists and marketing authorisation holder details are available in the UK patient information leaflet.
Patient information leaflet
The UK patient information leaflet for Spedra® is available via the electronic Medicines Compendium (eMC).
Frequently asked questions
How long does Spedra® take to work?
Spedra® takes effect within 15–30 minutes, though timing varies between men.
How long do the effects last?
The effects may last for up to six hours, lthough this varies between men.
Does Spedra® work without sexual stimulation?
No. Sexual stimulation is required for Spedra® to be effective.
Can I take Spedra® more than once per day?
No. Spedra® should not be taken more than once in a 24 hour period.
What makes Spedra® different from other ED medicines?
Spedra® contains avanafil, notable for its relatively rapid onset. It may take effect in as little as 15–30 minutes in some men, making it one of the faster-acting PDE-5 inhibitors available.
Can Spedra® be taken with food?
Yes. Spedra® can be taken with or without food.
Leaflet info
The Patient Information Leaflet (PIL) is the leaflet included in the pack with a medicine. It is written for patients and gives information about taking or using a medicine. It is possible that the leaflet in your medicine pack may differ from the PDF-version from this website because it may have been updated since your medicine was packaged or the medicine is from another brand.
