What is Priligy?
Priligy is a prescribed medication to treat premature ejaculation (PE) in men 18 to 64 years old. PE is a sensitive but very common sexual issue with one to two men in five suffering from this condition worldwide.
Priligy is a type of drug called a selective serotonin reuptake inhibitor (SSRI) which acts in the brain to help you increase your time to ejaculation and improve your control over ejaculation. Priligy has been scientifically proven to significantly increase the time you can last during sex.
The effect of Priligy lasts up to four hours after the tablet is taken and depending on the dose, it can double or triple the duration of sexual intercourse. This can therefore reduce any distress you may feel with PE concerning how fast you ejaculate.
Priligy is designed to delay your ejaculation so that both you and your partner feel improved satisfaction with sexual intercourse.
What is the active ingredient of Priligy?
Priligy contains the active ingredient dapoxetine hydrochloride and is categorised as a fast-acting selective serotonin reuptake inhibitor. Medicines in this drug class are also used to treat depression but they act slower than Priligy. Priligy is designed to give you a fast burst of serotonin which then leaves your body.
How does Priligy work?
Serotonin is a neurotransmitter or chemical messenger that passes messages between nerve cells in your body. Priligy is a selective serotonin reuptake inhibitor, which means that it acts in the brain to prevent the reuptake or absorption of serotonin by neurons (brain nerve cells). This results in increased levels of serotonin in the brain because it is kept around for longer before being absorbed by neurons. Increasing the activity of serotonin in the nervous system helps to increase the time it takes for you to ejaculate and improves your control over when you ejaculate.
Priligy works very quickly, so you can take it only when you anticipate having sex, rather than having to take it regularly every day. You need to take it one to three hours before you have sex.
Who can take Priligy?
Priligy is prescribed for men with premature ejaculation between the ages of 18 and 64 only who have all of the following:
- Ejaculation in less than 2 minutes following vaginal penetration, on most occasions, with little stimulation and before the man wishes to
- Marked personal distress and interpersonal difficulty as a result of premature ejaculation (premature ejaculation can trouble you and your partner)
- Poor control over ejaculation
- A history of premature ejaculation in the majority of intercourse attempts over the previous 6 months
Priligy is only to be taken when needed on an 'on-demand' basis before anticipated sexual activity. Priligy should not be prescribed to delay ejaculation in men who have not been diagnosed with PE.
What doses of Priligy are available?
Priligy comes in two strengths:
- Priligy 30 mg
- Priligy 60 mg
The recommended starting dose for all men prescribed with Priligy is 30 mg, taken as needed approximately 1 to 3 hours before sexual activity. Most men find that 30 mg is sufficient to treat PE and improve their sexual health. You should not start treatment with Priligy on the higher 60 mg dose.
Make sure that you make follow-up appointments with your doctor once you have been prescribed Priligy. If you find that the 30 mg dose is not working sufficiently for you and you haven’t experienced any bad side-effects, your doctor can increase your prescribed dose to the maximum recommended dose of 60 mg.
Note that the incidence and severity of side-effects are higher with the 60 mg dose.
How to take Priligy?
Before you start treatment with Priligy, read the information leaflet that comes with your medicine and make sure you take your medication according to your doctor’s instructions.
Priligy tablets should be swallowed whole with at least one full glass of water about 1-3 hours before sex to reduce the chances of fainting. You can take it with or without food.
Priligy is not intended for continuous daily use but rather as an ‘on demand’ medication when you anticipate you’re going to have sex soon. Do not take more than one tablet in 24 hours.
Priligy starts to work about an hour after taking a tablet and can last up to four hours.
See your doctor after the first 4 weeks or after 6 doses to see whether you should continue treatment. If you do continue, see your doctor again at least every six months.
Can I take Priligy and drink alcohol?
While taking Priligy, you should avoid drinking alcohol. This is because you can further exacerbate the effects of alcohol, such as feeling dizzy, sleepy and having slow reactions, when on Priligy.
Moreover, drinking alcohol while taking Priligy can increase your risk of injury from fainting or from other side effects.
What are the side effects of Priligy?
Priligy is effective in treating premature ejaculation but as with most medicines it can also cause some unwanted side effects in some people. Before taking Priligy, please read the manufacturer’s information leaflet that comes with your medicine which will give you the full list of its side effects.
Very common side effects affecting more than 1 in 10 men taking Priligy:
- Feeling dizzy or light-headed. If you experience this, sit with your head between your knees, or lie down until the feeling passes.
- Feeling nauseous, sweaty or confused. These are signed that you might faint so make sure you sit down until the feeling passes so that you do not fall and hurt yourself.
- Headache. If you suffer from a headache while on Priligy, drink plenty of water and see if you can take an over-the-counter painkiller.
Common side effects affecting between 1 in 10 and 1 in 100 men taking Priligy:
- Feeling anxious, irritable, restless or agitated
- Difficulty concentrating
- Blurred vision
- Feeling tired or sleepy
- Pins and needles or tingling sensations
- Ringing or other noise in the ears (tinnitus)
- Excessive sweating
- Difficulty sleeping (insomnia)
- Abnormal dreams
- Reduced sex drive
- Problems getting an erection (erectile dysfunction)
- Sinus congestion
- Disturbances for the gut such as diarrhoea, vomiting, constipation, abdominal pain and discomfort, indigestion, flatulence and dry mouth
- Increased blood pressure
If you suffer any of these side effects, or others that are not listed here, make sure you see your doctor or pharmacist to get advice.
When not to take Priligy?
Do not take Priligy if:
- You are allergic to dapoxetine or any of the other ingredients in Priligy
- You have heart problems
- You have a history of fainting
- You have ever had mania or severe depression
- You have moderate or severe liver problems.
- You are taking:
- Medicines for depression called ‘monoamine oxidase inhibitors’ (MAOIs)
- Thioridazine used for schizophrenia
- Other medicines for depression
- Lithium - a medicine for bipolar disorder
- Linezolid - an antibiotic used to treat infections
- Tryptophan - a medicine to help you sleep
- St John’s wort - a herbal medicine
- Tramadol - used to treat serious pain
- Medicines used to treat migraines
- Certain medicines for treating fungal infections
- Certain medicines for HIV
- Certain antibiotics
If you have taken any of these medicines, you can only start taking Priligy two weeks after you’ve stopped taking them. Also, you will need to wait a week before taking any of the above medicines after you have stopped taking Priligy. If you are not sure about what to do, talk to your doctor or pharmacist before taking Priligy.
Any specific warnings?
Do not drive or operate machinery if you feel tired or sleepy while taking Priligy. Also avoid drinking grapefruit juice within 24 hours before taking Priligy as this can increase the level of this medicine in your body.
Talk to your doctor before taking Priligy if:
- You have not been diagnosed with premature ejaculation
- You also have another sexual problem, such as erectile dysfunction
- You have a history of dizziness from low blood pressure
- You use recreational drugs
- You drink alcohol
- You have ever had a mental health problem such as depression, mania, bipolar disorder or schizophrenia (a psychiatric disease)
- You have epilepsy
- You have a history of bleeding or blood clotting problems
- You have kidney problems
- You have, or are at risk of, high pressure in the eye (glaucoma).
Before you start taking this medicine, your doctor should perform a test to make sure that your blood pressure doesn’t drop too much when you stand up from lying down.
The Patient Information Leaflet (PIL) is the leaflet included in the pack with a medicine. It is written for patients and gives information about taking or using a medicine. It is possible that the leaflet in your medicine pack may differ from the PDF-version from this website because it may have been updated since your medicine was packaged or the medicine is from another brand.