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Doxycycline is one of the well known antibiotics which treats a lot of different infections and malaria.
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The Patient Information Leaflet (PIL) is the leaflet included in the pack with a medicine. It is written for patients and gives information about taking or using a medicine. It is possible that the leaflet in your medicine pack may differ from the PDF-version from this website because it may have been updated since your medicine was packaged or the medicine is from another brand.
Doxycycline is one of the well known antibiotics which treats a lot of different infections.
It is one of the Tetracyclines, which belong to the huge group of antibiotics. Mostly people take Doxycycline cautionary before, while and after travelling into a Malaria affected region cause it provides people.
Doxycycline is only available with a prescription from a doctor. He or she makes sure that you are healthy and able to take this medicine. People who want to take Doxycycline must be older than 12 years as well. He also checks if the kind of Malaria in this area you are travelling to is defendable with this kind of tablet.
Fitting people for taking Doxycycline
Everyone who plans a trip into Malaria affected areas is appropriate for taking some protective tablets against the disease. Only kids younger than 12 years, pregnant or breast feeding woman should not take Doxycycline. Please recognize the chapter about warnings to make sure you are able to take Doxycycline without any risk.
The Effectiveness of the Treatment
The active component Doxycycline treats all kinds of Plasmodia very effective as long as you follow the instructions for the dose properly. But to protect your health as best as you can you should follow some simple rules to prevent malaria cause there is no medicine that is totally safe. Simple protection like insect repellent and clothes that protect you from mosquitos spend more safety. Symptoms of Malaria could be fever, nausea or headache. If you recognize any of those within your travel and for four more weeks after your trip you should seek for medical help as soon as possible.
Dose and Rules for taking Doxycycline
Each day while treating your disease with Doxycycline you should take a tablet with 100 mg of active component. You should start the treatment 2 days before your travel into an affected area starts. Take this one tablet a day as long as you stay in the malaria area and continue for four more weeks after your trip.
Should you forget one tablet once, take the missing one as soon as you remember. But don’t take two tablets too close to each other. If you remember the missing one very late, skip the dose and continue with the following one. But please remember that Doxycycline guarantees full protection only as long as you don’t miss any dose.
In case of sickness like vomiting or diarrhoea within one hour after taking a tablet, you should take one more tablet to guarantee full protection.
Some people taking Doxycycline feel stomach sickness while taking the tablets. If this is the case for you as well, try to take the dose with food. It has no influence on the treatment. To avoid problems at night take the tablet at least half an hour before going to bed.
Be careful with other ingredients you take during the treatment. Take Doxycycline at least two or three hours before taking substances containing calcium, aluminium, iron, magnesium, zinc or bismuth. Affected products could be enriched juices or mineral tablets. They disable the active component and stop the Doxycycline from being properly absorbed.
How to use Doxycycline?
Take as prescribed and consult the leaflet provided for more information.
Possible side effects of Doxycycline
Like all medicines, Doxycycline capsules can cause side effects, although not everybody gets them.
Stop taking the capsules immediately and seek urgent medical advice if:
• you notice that your skin is very sensitive to light (you may get a skin rash, itching, redness or severe sunburn when out in sunlight or after using a sun bed).
Contact your doctor at once if the following reactions happen:
• wheeziness, difficulty in breathing, fever, sudden swellings of the face, lips, throat, tongue, hands or feet, fast heart rate, low blood pressure, rash or itching (especially affecting the whole body), pericarditis (inflammation of the membrane surrounding the heart)
• swollen tongue, watery diarrhoea, fever and cramps (pseudomembranous colitis), soreness and itching around the back passage and/or genital areas, inflammation around the vagina, or thrush of the vagina or mouth
• worsening of systemic lupus erythematosus (SLE). Tell your doctor if you notice any of the following side effects or notice any other effects not listed:
• Blood: altered numbers of certain types of blood cells, you may notice that you bruise easily, have nose bleeds, or suffer from infections and sore throats, porphyria (sensitivity of the skin to sunlight, inflammation of nerves and stomach pains).
• Glands and hormones: discolouration of thyroid tissue (does not affect thyroid function).
• Central nervous system: headache, increased pressure in the skull (severe headaches, blurred and/or double vision, blind spots), permanent loss of vision, bulging fontanelles (soft spot on head) of infants.
• Ears: tinnitus (ringing or buzzing in the ears).
• Gastrointestinal tract: stomach pain, loss of appetite, feeling or being sick, heartburn, diarrhoea, difficulty swallowing, sore or painful tongue or mouth, inflammation and/or ulcers of the gullet, discolouration or underdevelopment of teeth.
• Liver: changes in liver function tests, inflammation of the liver (hepatitis), jaundice (yellowing of the skin or white of
the eyes), liver failure and inflammation of the pancreas (pancreatitis)
• Skin: severe skin reactions such as erythema multiforme (circular, irregular red patches), Stevens-Johnson syndrome (rash with flushing, fever, blisters or ulcers), toxic epidermal necrolysis (reddening, peeling and swelling that resembles burns), detachment of the nail from the finger bed.
• Muscles and bones: muscle or joint pain.
• Kidneys: an increase in urea in the blood.
A more detailed list of side effects can be found in the patient information.