What is Dalacin cream 2%?
Dalacin cream 2% is a type of antibiotic used to fight different types of infections that contains clindamycin phosphate as main component. It is mostly used either to treat acne or bacterial vaginosis BV.
It is mostly used when presence of certain bacteria are the cause o f bacterial vaginosis such as:
- Peptostreptococcus spp.
- Mucoplasma hominis
- Gardnerella vaginalis
- Bacteroides spp.
- Mobilincus spp.
Dalacin cream 2% comes in the form of a vaginal cream. It is white, semi-solid and contains 40 g of vaginal cream with 7 vaginal applicators.
What other excipients does Dalacin cream 2% vaginal cream contain?
Dalacin cream 2% also contains the following ingredients:
- Stearic acid
- Benzyl alcohol
- Liquid paraffin
- Sorbitan stearate
- Cetostearyl alcohol
- Polsorbate 60
- Cetyl palmitate
- Propylene glycol
What is Dalacin cream 2% used for?
Dalacin is a prescribed antibiotic, therefore it can not be used as over the counter medicine. It is mainly used for treating acne or bacterial vaginosis (BV).
What is Bacterial Vaginosis?
Bacterial Vaginosis is a type of inflammation in your vagina caused by the multiplication and overgrowth of the microorganisms that are naturally found in your vagina, called Lactobacilli. It is also known as nonspecific vaginitis.
Commonly known as BV, is considered to be one of the most common vaginal affection in women of reproductive age (14-49 years old). Normally, the vaginal flora consists of different microorganisms, being one of the most important Lactobacilli. Lactobacili have different sub-types and are different according to your ethnicity. These microorganisms maintain your vagina in an acidic environment (pH levels), preventing harmful bacteria to reproduce. When this barrier fails, “bad” bacteria start multiplying and that’s when the bacterial vaginosis occurs.
What are the risk factors of contracting BV?
Changes in your body: Pregnancy can lead to a higher prevalence and it is found that around 7-22% of pregnant women will suffer from this condition.
- Multiple sexual partners throughout your lifetime
- New sexual partner.
- Birth control devices such as IUD (intrauterine device)
- Vaginal hygiene products that contain perfume: vaginal deodorants, perfumed bubble baths
- Vaginal douches
- Use of strong detergents to wash underwear
- Tight clothing such as underwear or pants.
- Underwear made out of synthetic fibers.
- History of induced abortion
- Recent antibiotic treatment for other infections.
- Recent studies have identified vitamin D deficiency as a risk factor in pregnant women
- BV can be associated with hormonal factors since it develops most often around the time of menstruation, and may resolve spontaneously mid-cycle.
- Natural lack of Lactobacilli.
It is important to know that bacterial vaginosis can’t be transmitted from using public toilet seats, swimming pools, bed sheets or through contact.
Sexual activity has an indirect role in this disease. Women who have never had any type of sexual intercourse including oral, vaginal or anal sex can still be affected by this disease, but the prevalence of BV has a significant increase based on the number of sexual partners throughout your lifetime.
What are the signs and symptoms of BV?
The most common symptoms are usually recognized after sexual intercourse and include:
- Distinctive “fish-like” vaginal odor
- Increase in vaginal discharge
- Change in color of vaginal discharge: White to grayish color.
- Vulvar irritation or itching
- Burning pee sensation or pain decrease in the amount of urine. ( Less commonly.)
What are the complications if you don’t get treated?
BV can be spontaneously cure because of the hormonal changes that occur throughout your menstrual cycle, but it is important to take certain precautions and use medicine so that complications do not develop and mostly in pregnant women.
Some of the complications are:
- Susceptibility to other sexually transmitted infections such as chlamydia, gonorrhea, HIV, herpes simplex virus and others.
- Pelvic Inflammatory disease: also known as PID, is a complication of sexually transmitted disease that affects the uterus and Fallopian tubes that increase the risk of being infertile.
- Cervicitis: inflammation of the cervix, usually goes hand in hand with other infections such as gonorrhea, chlamydia and HSV (herpes simplex virus)
- Endometritis: Inflammation of the endometrium which can cause abnormal bleeding
- Higher predisposition to suffer from urinary tract infections
- Spontaneous abortions
- Salpingitis: inflammation of Fallopian tubes
- Bacteremia: Presence of bacteria in the bloodstream
When should you visit a doctor?
You should make an appointment with your doctor if you
- notice that your vaginal discharge is different in color and or smell
- presence of fever
- you’ve tried over the counter medicines and symptoms are still persistent
- if you present the symptoms and have a new sexual partner
- if you have had vaginal infections in the past but this time it appears different
- if you are pregnant or plan to get pregnant
- if you are breastfeeding
- if you experience abdominal or pelvic pain
Should you be tested for other sexually transmitted diseases?
Since bacterial vaginosis tends to increase the percentage of acquiring a sexually transmitted disease it is recommended for women to be tested for other infections such as gonorrhea, chlamydia, herpes simplex virus (HSV) and HIV depending on the life style habits and risk factors present in the patient.
It is important to know that chronic use of metronidazole or clindamycin may alter the flora found in the vagina which may lead to a predisposition to vaginal candidiasis.
Who should consider other alternatives over Dalacin cream 2%?
Clindamycin has a Black Box Warning because different cases of pseudomembranous colitis have been reported after using any type of clindamycin, be it orally, perenteral or topical administration. Therefore, special precautions should be taken if you present diarrhea after starting to use this medicine.
You should consider other alternatives if you have or suffer from:
- Hypersensitivity to clindamycin or any other of the other excipients Dalacin cream 2% contains.
- History of ulcerative colitis, antibiotic related colitis or regional enteritis.
- History of inflammatory bowel disease.
- Women who use condoms as a contraceptive should take extra precautions because the oil-based components of Dalacin cream weaken the rubber of either diaphragms or condoms. Therefore, it is advisable to use a different type of contraceptive method while using this treatment.
- No to be used in children less than 12 years of age.
- If you have your period or are about to start your menstrual cycle.
Are there medicines that have interactions with Dalacin cream 2%?
Just like all other medicines, there are certain medications that produce interactions with Dalacin cream 2%. Be sure to tell your doctor if you are taking any of the following medicines so that a proper adjustment of the treatment be made.
- Antibiotics: Erythromicin.
- Anticoagulant therapy: Warfarin, acenocoumarol and diuindione.
- Neuromuscular blocking agents: Used in anesthesia. Atracurium, pancuronium, rapacuronium, rocuronium, cisatracurium, succinylcholine, vecuronium and tubocrarine.
- Contraceptive pills: The efficacy of different contraceptive pills may be decreased, therefore it is advisable to use different types of contraceptive methods.
- Levonorgestrel, ethinylestradiol.
How should you use Dalacin cream 2%?
The usual adult dosage is 5 g (one applicator) inserted into the vagina, once a day before bedtime for seven days. A shorter treatment may be used depending on the symptoms for a course of 3 consecutive days. Be sure to use this medication as prescribed by your GP.
Before using Dalacin cream 2%, be sure to wash your hands thoroughly with water and soap. Every applicator is disposable, therefore it should only be used once for each dose. Squeeze the gel from the tube to insert it in the applicator. After removing it from the tube, insert the applicator into the vagina and push the gel inside. After using the applicator, discard it in the trash bin.
Can Dalacin cream 2% be used in pregnant or breastfeeding women?
If you are pregnant or breastfeeding be sure to tell your GP about it so that the dosage or medication is changed according to your situation. Studies have not shown adverse effects in pregnant women using clindamycin after first trimester but there are no studies made with Dalacin cream 2%. Precaution should be taken if you are pregnant or breastfeeding because it may cause adverse effects on the gastrointestinal flora of your baby such as diarrhea and colitis or dermatological effects such as candidiasis or diaper rash.
Should your sexual partner be treated as well if you were diagnosed with BV?
It is not necessary for your sexual partner to be treated if he/she does not present any symptoms, so no prophylactic treatment is necessary for this disease.
What should you do if you miss a dose?
If you miss a dose of Dalacin 2% cream, be sure to apply it as soon as you remember. If you are close to using the next dosage, do not use double the dosage to try to make up for the forgotten one. Continue your treatment as stated. Be sure to use your medications every day at the same hour to avoid forgetting any dosage. Since probable vaginal secretion is expected, it is recommended to be used at night. If you forgot to use an applicator, you can take other precautions such as using pads to avoid uncomfortable incidents such as secretion.
When should you stop taking the medication?
Always take the medication as prescribed by your doctor. Never stop the regimen just because you feel better or your discharge has stopped. This will lead to recurrent bacterial vaginosis or bacterial antibiotic resistance that will lead to complications.
What should you do if you took the medicine and the symptoms didn’t disappear?
Recurrent symptoms after 3 months are common in around 30% of women who suffer from bacterial vaginosis and 50% of women may present it in the upcoming 6 months. A 7 day oral or vaginal cream treatment may be used. Either Metronidazole or Clindamycin should work, with the only exception that if the first time you took metronidazole orally, next time change the treatment to Clindamycin in cream prospective and vice-versa. Be sure to visit your doctor if you present more than three bacterial vaginosis episodes in between 12 months, since the treatment will have to change.
Is there a risk of overdose by using Dalacin 2% cream?
Dalacin cream 2% main component is absorbed by the mucosa of the vagina and may produce in rare cases systemic effects. If you present systemic symptoms such as difficulty to breath, shortened breath, and or dizziness, be sure to seek medical help.
Dalacin cream 2% should only be used as prescribed, therefore should not be used near the eyes or swallowed, therefore should be kept out of reach of children. If you or anyone you know happens to accidentally swallow this medication, be sure to seek medical help.
Like all medicines, this medicine can cause side effects, although not everybody gets them.
Very Common side effects, (affecting less than 1 in every 10 patients):
- Inflammation of the Cervix
Common side effects, (affecting less than 1 in every 10 patients):
- Vaginal thrush
- Infection or inflammation of the vulva and vagina
- Vaginal disorder, Vaginal discomfort, vaginal discharge
- Stomach cramps
Uncommon (affecting less than 1 in every 100 patients)
- Inflammation of the Vagina
- Vaginal infection, urinary tract infection
- Yeast Infection ( body)
- Fungal Infection
- Allergic reactions
- Headache, dizziness
- A sensation of whirling and loss of balance, nosebleed
- Bad breath, diarrhoea, feeling sick (nausea), vomiting, change of sense of taste
- Constipation, stomach ache
- Upset Stomach or indigestion
- Passing wind
- Rash, reddening of the skin, hives
- Painful urination, excess of Sugar in the Urine, protein in the urine
- Vaginal pain
The Patient Information Leaflet (PIL) is the leaflet included in the pack with a medicine. It is written for patients and gives information about taking or using a medicine. It is possible that the leaflet in your medicine pack may differ from the PDF-version from this website because it may have been updated since your medicine was packaged or the medicine is from another brand.