The active component in Champix is Varenicline Tartrate.
Pfizer is the well-known pharmacy company behind Champix. This drug is made for people longing for quitting smoking. It works while stimulation receptors for nicotine in the brain of an addicted person and switches the longing for smoking a cigarette so that it becomes less attractive to smokers.
Champix could be a help for people who want to quit cause it makes it physically and psychologically easier to stop smoking.
Champix for quitting smoking
The drug Champix is made for people who tried to quit smoking before and failed a few times. This medicine helps smokers to quit easier and to get rid of the unloved habit. The active component in Champix is named Varenicline Tartrate based on herbal agents. Champix works without nicotine so you cannot get addicted to it instead of the cigarettes. But it influences some receptors in the brain. Therefore, it is only available with a prescription. It prevents the addictive effect nicotine has to you while smoking. Therefore smoking a cigarette becomes less attractive to you. Smoking doesn’t give you the full satisfaction you were used to so it becomes easier to quit.
The effect of Champix
Unlike other medication which claim to help quitting smoking Champix helps without the influence of nicotine. Therefore, Champix gives you the possibility to get really rid of your addiction to nicotine. Champix influences some receptors in your brain, which are responsible for your satisfaction after smoking. So Champix fights your physical and your psychological addiction to cigarettes.
Some receptors in the brain react every time they are influenced by nicotine. If the process starts the send messages to other brain areas which are responsible for spilling Dopamine. Dopamine is a hormone, which makes you feel happy and gives you the pleasure after smoking a cigarette. The dose of dopamine in the body rises and sinks after a short term. If this happens you start longing for another cigarette. Champix may help to break this circle.
Possible side effects of Champix
Like all medicines, this medicine can cause side effects, although not everybody gets them.
Giving up smoking with or without treatment can cause various symptoms. These could include changes of mood (like feeling depressed, irritable, frustrated or anxious), sleeplessness, difficulty concentrating, decreased heart rate and increased appetite or weight gain.
You should be aware of the possible emergence of serious neuropsychiatric symptoms, such as agitation, depressed mood, or changes in behaviour during a quit attempt with or without CHAMPIX and you should contact a doctor or pharmacist if you experience such symptoms.
Serious side effects of either an uncommon or rare frequency have occurred in people attempting to quit smoking with CHAMPIX: seizure, stroke, heart attack, suicidal thoughts, loss of contact witheality and unable to think or judge clearly (psychosis), changes in thinking or behaviour (such as aggression and abnormal behaviour). There have also been reports of severe skin reactions including Erythema Multiforme (a type of rash) and Stevens-Johnson Syndrome (a serious illness with blistering of the skin, mouth, around the eyes or genitals) and serious allergic reactions including angioedema (swelling of the face, mouth, or throat).
Very common: may affect more than 1 in 10 people
- Inflammation of the nose and throat, abnormal dreams, difficulty sleeping, headache,
Common: may affect up to 1 in 10 people
- Chest infection, inflammation of the sinuses
- Increased weight, decreased appetite, increased appetite
- Sleepiness, dizziness, changes in the way things taste
- Shortness of breath, cough
- Heartburn, vomiting, constipation, diarrhoea, feeling bloated, abdominal pain, toothache, indigestion, flatulence, dry mouth
- Skin rash, itching
- Joint ache, muscle ache, back pain
- Chest pain, tiredness
Uncommon: may affect up to 1 in 100 people
- Fungal infection, viral infection
- Feeling of panic, difficulty thinking, restlessness, mood swings, depression, anxiety, hallucinations, changes in sex drive
- Seizure, tremor, feeling sluggish, less sensitive to touch
- Conjunctivitis, eye pain
- Ringing in the ears
- Angina, rapid heart rate, palpitations, increased heart rate
- Increased blood pressure, hot flush
- Inflammation of nose, sinuses and throat, congestion of nose, throat and chest, hoarseness, hay fever, throat irritation, congested sinuses, excess mucous from nose causing cough, runny nose
- Red blood in stools, irritated stomach, change of bowel habit, belching, mouth ulcers, pain in the gums
- Reddening of the skin, acne, increased sweating, night sweats
- Muscle spasms, chest wall pain
- Abnormally frequent urination, urination at night
- Increased menstrual flow
- Chest discomfort, flu like illness, fever, feeling weak or unwell
- High blood sugar
- Heart attack
- Suicidal thoughts
- Changes in thinking or behaviour (such as aggression)
Rare: may affect up to 1 in 1,000 people
- Excessive thirst
- Feeling unwell or unhappy, slow thinking
- Increased muscle tension, difficulty with speech, difficulty with coordination, reduced sense of taste, altered sleep pattern
- Disturbed vision, eyeball discolouration, dilated pupils, sensitivity to light, shortsightedness, watery eyes
- Irregular heart beat or heart rhythm disturbances
- Throat pain, snoring
- Blood in vomit, abnormal stools, coated tongue
- Stiff joints, rib pain
- Glucose in urine, increased urine volume and frequency
- Vaginal discharge, changes in sexual ability
- Feeling cold, cyst
- Sleep walking
- Loss of contact with reality and unable to think or judge clearly (psychosis)
- Abnormal behaviour
- Severe skin reactions including Erythema Multiforme (a type of rash) and Stevens-Johnson Syndrome (a serious illness with blistering of the skin, mouth, around the eyes or genitals)
- Serious allergic reactions including angioedema (swelling of the face, mouth, or throat)
A more detailed list of side effects can be found in the patient information.
The Patient Information Leaflet (PIL) is the leaflet included in the pack with a medicine. It is written for patients and gives information about taking or using a medicine. It is possible that the leaflet in your medicine pack may differ from the PDF-version from this website because it may have been updated since your medicine was packaged or the medicine is from another brand.